<p>ST. LOUIS — Jesse Winker hit a two-run homer, Vladimir Gutiérrez earned his first career win and the Cincinnati Reds beat the St. Louis Cardinals 4-2 on Thursday night.</p>
<p>Gutiérrez (1-1) pitched five innings of two-run ball, settling down nicely after a shaky start. He allowed three hits, struck out three and walked three in his second big league game.</p>
<p>Tejay Antone followed Gutiérrez with two scoreless innings, and Lucas Sims got six outs for his fourth save.</p>
<p>St. Louis got two in the first on RBI singles by Tyler O’Neill and Yadier Molina. O’Neill extended his hitting streak to a career-best 11 games.</p>
<p>But Cincinnati went ahead to stay on Winker’s 14th homer in the second, a drive to right against Adam Wainwright that traveled an estimated 425 feet.</p>
<p>Winker finished with three hits, and Nick Castellanos extended his hitting streak to 19 games with a first-inning single. Tucker Barnhart added an RBI double in the eighth.</p>
<p>Wainwright (3-5) permitted three runs and eight hits in seven innings. He hit a career-high three batters, including Tyler Naquin with the bases loaded in the first inning.</p>
<p>The Cardinals lost for the fourth time in five games.</p>
<p>Wainwright got some help from his defense in the fifth when Dylan Carlson, Tommy Edman and Molina executed a perfect 8-4-2 putout on Tyler Stephenson as he tried to score on a Naquin double.</p>
<p>MOVING UP</p>
<p>Wainwright and Molina made their 284th career start as batterymates, passing Don Drysdale and John Roseboro (1957-67) of the Dodgers for fourth all-time in major league history since records were kept in 1908. </p>
<p>MISSING FIRST BASEMEN</p>
<p>Both teams were without their All-Star first basemen in the starting lineup. Paul Goldschmidt was given a night off by the Cardinals, while the Reds’ Joey Votto (broken left thumb) started a rehab assignment in Triple-A Louisville on Wednesday.</p>
<p>Goldschmidt drew a pinch-hit walk in the bottom of the ninth.</p>
<p>TRAINING ROOM</p>
<p>Reds: OF Aristides Aquino (left hamate fracture) was sent to Louisville for a rehab assignment.</p>
<p>Cardinals: LHP Andrew Miller (toe) was activated from the 10-day injured list, and LHP Tyler Webb was designated for assignment.</p>
<p>UP NEXT</p>
<p>Reds right-hander Luis Castillo (1-8, 7.22 ERA) starts Friday night against Cardinals left-hander Kwang Hyun Kim (1-3, 3.65 ERA). Castillo is seeking his first win since April 7. Kim is making his fourth career start against Cincinnati after winning his first three outings.</p>
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